MTHFS

Description

The MTHFS gene provides instructions for making methylenetetrahydrofolate reductase (MTHFR), an enzyme that plays a crucial role in folate metabolism. Folate, a B vitamin, is essential for DNA synthesis and repair, cell division, and the production of red blood cells. MTHFR converts dihydrofolate to tetrahydrofolate, a coenzyme required for numerous metabolic processes. This gene‘s function is crucial for maintaining normal development and overall health.

Associated Diseases

• Neural tube defects (NTDs)
• Hyperhomocysteinemia
• Cardiovascular disease
• Depression
• Cancer
• Infertility

Did you know?

Variations in the MTHFS gene are common and can affect enzyme activity, leading to altered folate metabolism.