MGME1

Description

The MGME1 gene provides instructions for making a protein called mitochondrial membrane protein of 22 kDa (MGME1). This protein is crucial for the proper function of mitochondria, the powerhouses of our cells. MGME1 plays a critical role in mitochondrial protein import, a process where proteins are transported into the mitochondria to perform their essential functions. This protein is located in the inner mitochondrial membrane and interacts with other proteins to ensure the efficient and accurate import of essential mitochondrial proteins.

Associated Diseases

• Leigh syndrome
• Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS)
• Myoclonic epilepsy with ragged-red fibers (MERRF)
• Cardiomyopathy
• Deafness

Did you know?

Mutations in the MGME1 gene are responsible for a wide range of mitochondrial disorders, highlighting the critical role of this protein in cellular function.