KIF7 : kinesin family member 7

Description

The KIF7 gene encodes a protein essential for proper embryonic development. KIF7 plays a critical role in regulating cell proliferation, differentiation, and migration during various developmental stages. Its function is tightly linked to the Hedgehog (Hh) signaling pathway, a crucial regulator of embryonic patterning and organogenesis. Mutations in KIF7 can disrupt these processes, leading to a spectrum of developmental disorders. Understanding the intricate roles of KIF7 in development and disease holds significant promise for advancing diagnostics and therapeutic strategies.

Associated Diseases

• Joubert Syndrome
• Meckel-Gruber Syndrome
• Orofaciodigital Syndrome type 1
• Hydrolethalus Syndrome
• Sensenbrenner Syndrome

Did you know?

KIF7 is named after its role as a kinesin, a motor protein involved in intracellular transport. The ‘KIF‘ prefix stands for ‘kinesin family member.‘