FBXL4 : F-box and leucine rich repeat protein 4

Description

FBXL4 (F-box and leucine-rich repeat protein 4) is a gene that encodes a protein involved in the ubiquitin-proteasome system (UPS), a cellular pathway responsible for degrading damaged or unnecessary proteins. FBXL4 plays a crucial role in regulating various cellular processes, including cell cycle progression, DNA repair, and immune responses. Mutations or dysregulation of FBXL4 can lead to several human diseases, highlighting its importance in maintaining cellular homeostasis.

Associated Diseases

• Cancer (e.g., leukemia, lymphoma, breast cancer)
• Neurological disorders (e.g., Parkinson‘s disease, Alzheimer‘s disease)
• Immune system disorders (e.g., autoimmune diseases)

Did you know?

FBXL4 has been implicated in the regulation of circadian rhythm, the natural sleep-wake cycle.