DDHD1

Description

DDHD1 (Diacylglycerol Diacylglycerol Lipase 1) is a gene that encodes an enzyme involved in lipid metabolism. This enzyme, known as DDHD1, plays a critical role in the hydrolysis of diacylglycerol (DAG), a key signaling molecule in cellular processes. DDHD1's activity is particularly important in the brain, where it influences neuronal function and lipid homeostasis. Mutations in the DDHD1 gene have been linked to various neurological disorders, highlighting its significance in maintaining healthy brain function.

Associated Diseases

• Spinocerebellar ataxia type 37 (SCA37)
• Intellectual disability
• Epilepsy
• Autism spectrum disorder

Did you know?

DDHD1 is highly expressed in the brain, particularly in regions associated with learning and memory, such as the hippocampus and cortex.