CCT5
Description
CCT5, also known as TCP-1 epsilon, is a gene encoding a subunit of the chaperonin containing TCP-1 (CCT) complex. This complex plays a vital role in the proper folding of a wide range of proteins, particularly those involved in cytoskeletal assembly, cell signaling, and stress response. CCT5, along with other CCT subunits, forms a barrel-shaped structure that interacts with unfolded proteins, promoting their correct folding and preventing misfolding and aggregation. Mutations in CCT5 can disrupt this process, leading to various cellular dysfunctions and disease.
Associated Diseases
Did you know?
The CCT complex is highly conserved across various species, highlighting its fundamental importance for protein homeostasis.
