ACADS : acyl-CoA dehydrogenase short chain
Short-Chain Acyl-CoA Dehydrogenase: The Key to Energy from Fats
Description
The gene known as ACADS holds the blueprint for producing an enzyme called short-chain acyl-CoA dehydrogenase (SCAD). This enzyme, like a skilled worker within the powerhouses of our cells, the mitochondria, is indispensable for breaking down fats into usable energy.
Associated Diseases
Defects in the ACADS gene can lead to a rare but potentially severe metabolic disorder known as short-chain acyl-CoA dehydrogenase deficiency (SCADD). Individuals with SCADD struggle to convert short-chain fatty acids into energy, resulting in accumulation of these fats in the body. Infants with SCADD may experience low blood sugar, liver dysfunction, heart problems, and even seizures.
Did you Know ?
Short-chain fatty acids account for approximately 10% of the energy needs of the heart and skeletal muscles, highlighting their importance in fueling these vital organs.
