Protein kinase B (PKB), involved in cell proliferation, survival, metabolism, and angiogenesis.

Associated Diseases

Several types of cancer, including breast, colorectal, ovarian, and lung cancers.

Did you know

Estimated prevalence AKT1 mutations appears to be lower,  from less than 1% to around 3-5%. The AKT1 gene, also known as protein kinase B (PKB), is a key regulator of various cellular processes such as cell proliferation, survival, metabolism, and angiogenesis. It plays a crucial role in several signaling pathways, including the PI3K/AKT/mTOR pathway, which is frequently dysregulated in cancer and other diseases.

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