ACE

Description

The angiotensin-converting enzyme (ACE) gene plays a crucial role in regulating blood pressure by influencing the renin-angiotensin-aldosterone system (RAAS). This system controls blood volume and pressure through the production and regulation of angiotensin II, a potent vasoconstrictor. The ACE gene encodes for the ACE enzyme, which converts angiotensin I to angiotensin II. Variations in the ACE gene can affect enzyme activity, leading to different levels of angiotensin II production and ultimately influencing blood pressure.

Associated Diseases

• Hypertension (high blood pressure)
• Cardiovascular disease (heart disease, stroke)
• Kidney disease
• Preeclampsia (a pregnancy complication)
• Diabetes
• Asthma

Did you know?

The ACE gene is located on chromosome 17 and has been linked to athletic performance, particularly in endurance sports.