GDPD2
Description
The GDPD2 (glycerophosphodiester phosphodiesterase domain containing 2) is a protein-coding gene located on chromosome X.
GDPD2 exhibits glycerophosphoinositol inositolphosphodiesterase activity, specifically breaking down glycerophosphoinositol. It does not act on other substrates like glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, or glycerophosphoserine. GDPD2 promotes osteoblast differentiation and growth. It is thought to be involved in the reorganization of the actin cytoskeleton.
GDPD2 is also known as GDE3, OBDPF.
Associated Diseases
- glycogen storage disorder due to hepatic glycogen synthase deficiency
 - diabetes mellitus, permanent neonatal 4
 - diabetes mellitus, transient neonatal, 3
 - transient neonatal diabetes mellitus
 - colorectal cancer
 - COVID-19
 - cancer