GABRR2
Description
The GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2) is a protein-coding gene located on chromosome 6.
Gamma-aminobutyric acid receptor subunit rho-2 is a protein encoded by the GABRR2 gene in humans. GABA is the main inhibitory neurotransmitter in the mammalian brain, acting on GABA receptors, which are ligand-gated chloride channels. GABRR2 belongs to the rho subunit family.
GABA, the primary inhibitory neurotransmitter in the vertebrate brain, regulates neuronal activity by binding to GABA/benzodiazepine receptors, opening chloride channels. The Rho-2 GABA receptor may contribute to retinal neurotransmission.
GABRR2 is also known as -.
Associated Diseases
- thyroid gland adenocarcinoma
- esophageal cancer
- 46,XY complete gonadal dysgenesis
- 8p23.1 microdeletion syndrome
- isolated congenital hypogonadotropic hypogonadism
- 46,XY partial gonadal dysgenesis
- 46,XX ovotesticular disorder of sex development
- spermatogenic failure, X-linked, 2
- alcohol dependence
- bipolar disorder
- Rett syndrome
- migraine disorder
