GABRR1

Description

The GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1) is a protein-coding gene located on chromosome 6.

Gamma-aminobutyric acid receptor subunit rho-1 is a protein encoded by the GABRR1 gene in humans. GABA, the main inhibitory neurotransmitter in the mammalian brain, acts on GABA receptors, which are ligand-gated chloride channels. GABRR1 belongs to the rho subunit family. GABAA-ρ receptor is another name for this receptor.

GABA, the primary inhibitory neurotransmitter in the vertebrate brain, exerts its inhibitory effects by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor is thought to play a role in retinal neurotransmission.

GABRR1 is also known as -.

Associated Diseases

• refractive error
• esophageal cancer
• alcohol dependence
• migraine disorder
• achalasia-alacrima syndrome
• myopia