FYTTD1
Description
The FYTTD1 (forty-two-three domain containing 1) is a protein-coding gene located on chromosome 3.
FYTTD1 is essential for the movement of messenger RNA (mRNA) from the nucleus, the cell's control center, to the cytoplasm, the cell's working area. It acts as a connector, using the DDX39B/UAP56-NFX1 pathway to ensure that mRNA is efficiently transported and delivered to the nuclear pore, the gateway between the nucleus and the cytoplasm. FYTTD1 also interacts with ALYREF/THOC4, a protein involved in mRNA processing, and binds to both spliced and unspliced mRNAs.
FYTTD1 is also known as UIF.
Associated Diseases
- hemoglobin E-beta-thalassemia syndrome
- hemoglobin D disease
- hemoglobin E disease
- dominant beta-thalassemia
- pentosuria
- congenital dyserythropoietic anemia type 4
- Alzheimer disease
- pancreatic ductal adenocarcinoma
