FXYD5
Description
The FXYD5 (FXYD domain containing ion transport regulator 5) is a protein-coding gene located on chromosome 19.
FXYD5, also known as Dysadherin or RIC, is a protein encoded by the FXYD5 gene. It belongs to a family of small membrane proteins sharing a common signature sequence. This family regulates ion transport, and members like FXYD1, FXYD2, FXYD3, and FXYD4 have been shown to influence channel activity. Dysadherin acts as the gamma5 subunit of the human Na,K-ATPase, a vital enzyme responsible for maintaining sodium and potassium ion gradients across the cell membrane. Two transcript variants exist for FXYD5, both predicted to encode the same protein.
FXYD5 is also known as DYSAD, HSPC113, IWU1, KCT1, OIT2, PRO6241, RIC.
