FPGT-TNNI3K
Description
The FPGT-TNNI3K (FPGT-TNNI3K readthrough) is a protein-coding gene located on chromosome 1.
The FPGT-TNNI3K fusion gene arises from a chromosomal translocation, combining the FPGT and TNNI3K genes. This fusion gene encodes a chimeric protein composed of the N-terminal region of FPGT and the C-terminal region of TNNI3K. The specific function of this fusion protein is currently unknown, but it likely influences muscle development or function. Further investigations are required to understand its precise role and potential implications for cardiac health.
The FPGT-TNNI3K fusion gene, resulting from a chromosomal translocation, encodes a chimeric protein with a potential role in muscle development and function. The fusion protein combines the N-terminal domain of FPGT, a protein involved in sugar metabolism, with the C-terminal domain of TNNI3K, a cardiac troponin I isoform. However, the precise functional implications of this fusion remain unclear. Further research is needed to elucidate its exact role in muscle cells and its potential impact on cardiac health.
FPGT-TNNI3K is also known as CARK, TNNI3K.
