FOXC2 : forkhead box C2
Description
The FOXC2 (forkhead box C2) is a protein-coding gene located on chromosome 16.
The FOXC2 gene provides instructions for making a protein that plays a critical role in the formation of many organs and tissues before birth. This protein is a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity of many other genes. Researchers believe that the FOXC2 protein has a role in a variety of developmental processes, such as the formation of veins and the development of the lungs, eyes, kidneys and urinary tract, cardiovascular system, and the transport system for immune cells (lymphatic vessels).
Transcriptional activator.
FOXC2 is also known as FKHL14, LD, MFH-1, MFH1.