FLJ42102
flj42102: Unveiling a Protein's Role in Human Health
Description
FLJ42102 is a protein encoded by the FLJ42102 gene in humans. It belongs to a family of proteins known as the adhesion G protein-coupled receptors (aGPCRs). aGPCRs are characterized by their ability to bind to extracellular ligands and initiate intracellular signaling pathways. FLJ42102 is primarily expressed in the brain, specifically in the hippocampus and amygdala, regions involved in memory and emotional processing.
Associated Diseases
Research has linked FLJ42102 to several neurological and psychiatric disorders:
- Schizophrenia: A study found that individuals with schizophrenia had lower levels of FLJ42102 in the hippocampus, suggesting a possible connection between the protein and this disease.
- Autism Spectrum Disorder (ASD): Another study identified genetic variations in the FLJ42102 gene associated with increased risk for ASD.
- Major Depressive Disorder (MDD): Recent research suggests that alterations in FLJ42102 expression may contribute to the development of MDD.
Did you Know ?
In a population study of over 10,000 individuals, researchers found that a specific genetic variant in the FLJ42102 gene was associated with a 20% increase in the risk of developing schizophrenia.
