FGF17
Description
The FGF17 (fibroblast growth factor 17) is a protein-coding gene located on chromosome 8.
Fibroblast growth factor 17 (FGF17) is a protein encoded by the FGF17 gene in humans. It belongs to the fibroblast growth factor (FGF) family, known for their diverse roles in cell growth, development, and tissue repair. FGF17 is highly expressed in the cerebellum and cortex, suggesting its importance in brain development. Research on the mouse counterpart of FGF17 has revealed its presence in specific areas of the forebrain, midbrain-hindbrain junction, developing skeleton, and arteries, implying its role in brain, bone, and vascular development. Though initially designated as FGF-13 in some publications, its amino acid sequence and chromosomal location match those of FGF17.
FGF17 is also known as FGF-13, FGF-17, HH20.
Associated Diseases
- Hypogonadotropic hypogonadism 20 with or without anosmia
- Kallmann syndrome
- Normosmic congenital hypogonadotropic hypogonadism
- Hypogonadotropic hypogonadism 7 without anosmia