FBXL8
Description
The FBXL8 (F-box and leucine rich repeat protein 8) is a protein-coding gene located on chromosome 16.
FBXL8 acts as a substrate recognition component within the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex.
FBXL8 is also known as FBL8.
Associated Diseases
- early-onset zonular cataract
- cataract 5 multiple types
- cancer
- neutropenia-monocytopenia-deafness syndrome
- neutropenia, severe congenital, 2, autosomal dominant
- X-linked severe congenital neutropenia
- neutropenia, severe congenital, 1, autosomal dominant
- cataract
- nonpapillary renal cell carcinoma
