FABP2
Description
The FABP2 (fatty acid binding protein 2) is a protein-coding gene located on chromosome 4.
FABP2, also known as Intestinal-type fatty acid-binding protein (I-FABP), is a protein encoded by the FABP2 gene. It belongs to a family of intracellular fatty acid-binding proteins (FABPs), which are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. FABPs may also be involved in cell growth and proliferation. FABP2 is an abundant cytosolic protein in small intestine epithelial cells. It has a polymorphism at codon 54 with two alleles: an alanine-encoding allele and a threonine-encoding allele. The Thr-54 protein is associated with increased fat oxidation and insulin resistance.
FABP2 is also known as FABPI, I-FABP.
