FABP1
Description
The FABP1 (fatty acid binding protein 1) is a protein-coding gene located on chromosome 2.
FABP1 is a human gene that encodes the protein FABP1 (Fatty Acid-Binding Protein 1), also known as liver-type fatty acid-binding protein (LFABP). It's primarily found in the liver and plays a key role in binding, transporting, and metabolizing long-chain fatty acids, endocannabinoids, phytocannabinoids, and other hydrophobic molecules. Changes in its expression have been linked to metabolic issues like obesity.
FABP1 was first discovered in 1972 through experiments that identified a soluble fatty acid carrier in the intestines responsible for absorbing long-chain fatty acids. Since then, ten members of the FABP family have been identified in the human genome. Each FABP is specific to certain organs and tissues, playing a part in fatty acid uptake, transport, and metabolism.
The FABP1 gene is located on chromosome 2, and its protein has a unique structure compared to other FABPs, enabling it to bind multiple ligands simultaneously.
FABP1 is also known as FABPL, L-FABP.
