ERP29
Description
The ERP29 (endoplasmic reticulum protein 29) is a protein-coding gene located on chromosome 12.
ERp29 is a chaperone protein that resides in the lumen of the endoplasmic reticulum (ER) and is involved in the processing of secretory proteins within the ER. While it shares sequence similarity with the protein disulfide-isomerase family, it lacks the thioredoxin motif characteristic of this family, suggesting that it does not function as a disulfide isomerase. The protein dimerizes and may play a role in protein folding within the ER. Multiple transcript variants encoding different isoforms result from alternative splicing.
ERP29 is also known as C12orf8, ERp28, ERp31, HEL-S-107, PDI-DB, PDIA9.
