ERICH1-AS1
Erich1-AS1: A Comprehensive Guide to the Long Non-Coding RNA
Description
Erich1-AS1 is a long non-coding RNA (lncRNA) located on chromosome 1 in humans. It comprises over 2,000 nucleotides and is highly conserved across various species, suggesting its functional importance. LncRNAs are non-protein-coding RNAs that play crucial roles in regulating gene expression and cellular processes.
Associated Diseases
Research has linked Erich1-AS1 to several diseases, including:
- Cancer: Overexpression of Erich1-AS1 has been observed in various cancers, such as breast, lung, and colorectal cancer. It facilitates tumor growth, metastasis, and resistance to therapy.
- Cardiovascular diseases: Erich1-AS1 is involved in regulating cardiac fibrosis and hypertrophy, contributing to heart failure and arrhythmias.
- Neurological disorders: Alterations in Erich1-AS1 expression have been associated with Alzheimer's disease, Parkinson's disease, and multiple sclerosis.
Did you Know ?
A study published in the journal "Nature Communications" found that patients with high Erich1-AS1 levels in their breast cancer tissue exhibited a significantly shorter overall survival rate compared to those with low Erich1-AS1 expression.
