EPCAM


The EPCAM gene encodes a protein known as Epithelial Cell Adhesion Molecule (EpCAM)

Associated Diseases

Lynch Syndrome

Did you know

Lynch syndrome, also known as hereditary non-polyposis colorectal cancer (HNPCC), is the most common cause of hereditary colorectal (colon) cancer.

People with Lynch syndrome are more likely to get colorectal cancer and other cancers, and at a younger age (before 50), including

  • Uterine (endometrial),
  • Stomach,
  • Liver,
  • Kidney,
  • Brain, and
  • Certain types of skin cancers.

Lynch syndrome is due to inherited changes (mutations) in genes that affect DNA mismatch repair, a process that fixes mistakes made when DNA is copied. These genes (MLH1MSH2MSH6PMS2, and EPCAM) normally protect you from getting certain cancers, but some mutations in these genes prevent them from working properly.


Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.