EPB41L3

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Description

The EPB41L3 (erythrocyte membrane protein band 4.1 like 3) is a protein-coding gene located on chromosome 18.

Band 4.1-like protein 3 is a protein that in humans is encoded by the EPB41L3 gene.

== Interactions == EPB41L3 has been shown to interact with YWHAB, YWHAH, YWHAG and Cell adhesion molecule 1.

EPB41L3 acts as a tumor suppressor, inhibiting cell proliferation and promoting apoptosis. It modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.

EPB41L3 is also known as 4.1B, DAL-1, DAL1.

Associated Diseases

• thyroid gland adenocarcinoma
• autosomal dominant sensory ataxia 1
• null syndrome
• leukoencephalopathy with calcifications and cysts
• Charcot-Marie-Tooth disease type 1C
• Pelizaeus-Merzbacher disease, classic form
• autosomal recessive spastic paraplegia type 71
• cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome
• spinocerebellar ataxia type 35
• Unverricht-Lundborg syndrome