EIF4G3
Description
The EIF4G3 (eukaryotic translation initiation factor 4 gamma 3) is a protein-coding gene located on chromosome 1.
EIF4G3 is a gene that encodes a protein involved in the translation process. The protein, also referred to as eIF4GII, helps assemble the ribosome onto the mRNA template, facilitating protein synthesis. It is similar to EIF4G1 and EIF4G2, but EIF4G2 is not a functional translation initiation factor. EIF4G3 has been shown to interact with PABPC1.
EIF4G3 is a component of the protein complex eIF4F, which plays a crucial role in the translation process. eIF4F is responsible for recognizing the mRNA cap, unwinding the secondary structure at the 5' end of the mRNA, and recruiting the mRNA to the ribosome. EIF4G3 is a functional homolog of EIF4G1, suggesting similar roles in translation.
EIF4G3 is also known as eIF-4G 3, eIF4G 3, eIF4GII.
