EIF3IP1
Description
The EIF3IP1 (eukaryotic translation initiation factor 3 subunit I pseudogene 1) is a pseudo gene located on chromosome 7.
EIF3IP1 is a gene that encodes a protein involved in translation initiation. This protein is part of the eukaryotic translation initiation factor 3 (eIF3) complex, which is essential for the assembly of the translation initiation complex and regulation of mRNA binding. EIF3IP1 also plays a role in the formation of stress granules, which are cytoplasmic aggregates that form under cellular stress conditions.
EIF3IP1 plays a crucial role in translation initiation by acting as a scaffold protein within the eukaryotic translation initiation factor 3 (eIF3) complex. This complex is essential for the recruitment of the 40S ribosomal subunit to the mRNA and subsequent assembly of the translation initiation complex. EIF3IP1, specifically, interacts with other eIF3 subunits and the small ribosomal subunit, contributing to the regulation of translation initiation and mRNA binding. It also participates in the formation of stress granules, cytoplasmic aggregates that form under cellular stress conditions, potentially influencing translation regulation during stress.
EIF3IP1 is also known as RG208K23.
