EID2B
Description
The EID2B (EP300 interacting inhibitor of differentiation 2B) is a protein-coding gene located on chromosome 19.
EID2B functions as a repressor, inhibiting the transcription of genes regulated by the MYOD transcription factor and the glucocorticoid receptor. This suppression ultimately leads to the inhibition of muscle differentiation.
EID2B is also known as EID-2B, EID-3.
Associated Diseases
- dehydrated hereditary stomatocytosis
- diabetes mellitus, permanent neonatal 4
- diabetes mellitus, transient neonatal, 3
- ghosal hematodiaphyseal dysplasia
- permanent neonatal diabetes mellitus 1
- 22q11.2 deletion syndrome
- familial pseudohyperkalemia
- autosomal recessive hypophosphatemic rickets
- Alzheimer disease
