EGR3

Description

The EGR3 (early growth response 3) is a protein-coding gene located on chromosome 8.

Early growth response protein 3 is a protein in humans, encoded by the EGR3 gene. The gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controlling biological rhythm. It may also play a role in muscle development.

EGR3 is also known as EGR-3, PILOT.

Associated Diseases

• schizophrenia
• glioblastoma
• autosomal recessive spondylocostal dysostosis
• spastic ataxia 2
• amyotrophic lateral sclerosis type 2, juvenile
• juvenile primary lateral sclerosis