ECT2L

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Description

The ECT2L (epithelial cell transforming 2 like) is a protein-coding gene located on chromosome 6.

ECT2L is a protein encoded by the ECT2L gene in humans. Recurrent mutations in this gene have been linked to cases of acute lymphoblastic leukemia.

May act as a guanine nucleotide exchange factor (GEF).

ECT2L is also known as ARHGEF32, C6orf91, FBXO49, LFDH, dJ509I19.2, dJ509I19.3, dJ509I19.5.

Associated Diseases

• urinary bladder carcinoma
• skin squamous cell carcinoma
• superficial spreading melanoma
• central nervous system primitive neuroectodermal neoplasm
• carcinoma of liver and intrahepatic biliary tract