DUSP15
Description
The DUSP15 (dual specificity phosphatase 15) is a protein-coding gene located on chromosome 20.
DUSP15 (Dual specificity protein phosphatase 15) is an enzyme that belongs to the non-receptor protein-tyrosine phosphatase family. This gene encodes a protein with both protein-tyrosine phosphatase and serine/threonine-specific phosphatase activity, hence it's classified as a dual specificity phosphatase. The DUSP15 gene has three transcript variants that produce two different protein isoforms.
DUSP15 has been shown to dephosphorylate several proteins, including MAPK13, ATF2, ERBB3, PDGFRB, and SNX6, suggesting its role in regulating their activity. This dephosphorylation activity is supported by evidence from a study published in PubMed (PMID:22792334).
DUSP15 is also known as C20orf57, VHY.
