DSCAS
Description
The DSCAS (DSC1/DSC2 antisense RNA) is a ncRNA gene located on chromosome 18.
DSCAM is a cell adhesion molecule that plays a crucial role in neuronal development, particularly in axon guidance and synapse formation. It exhibits remarkable diversity, resulting from alternative splicing, which allows it to generate a vast array of isoforms with unique binding properties. This diversity is essential for its function in mediating specific cell-cell interactions during the development of neural circuits. Mutations in DSCAM have been implicated in various neurodevelopmental disorders.
DSCAM is a cell adhesion molecule involved in neuronal development and axon guidance. It is expressed in various regions of the brain, including the cortex, hippocampus, and cerebellum. DSCAM plays a critical role in synapse formation and refinement, contributing to the precise wiring of neuronal circuits. Mutations in DSCAM have been linked to various neurodevelopmental disorders, highlighting its significance in brain function.
DSCAS is also known as -.
