DOPEY1
Dopey1: Delving into a Gene Linked to Intellectual Disability
Description
Dopey1, also known as ZNF644, is a gene located on chromosome 16q24.3 in humans. It encodes a protein that plays a crucial role in the development and function of the central nervous system. Dopey1 is involved in a variety of cellular processes, including gene regulation, protein synthesis, and neuron differentiation.
Associated Diseases
Dopey1 mutations have been linked to a range of intellectual disability syndromes, including:
- Developmental and epileptic encephalopathy: A condition characterized by severe developmental delays, intellectual disability, and seizures.
- Autism spectrum disorder (ASD): A complex developmental condition that affects social interaction, communication, and behavior.
- Schizophrenia: A severe mental illness that affects perception, thinking, and behavior.
- Attention deficit hyperactivity disorder (ADHD): A neurodevelopmental disorder characterized by difficulty paying attention, hyperactivity, and impulsivity.
Did you Know ?
- Mutations in Dopey1 are estimated to occur in approximately 1 in 100,000 individuals worldwide.
