DNASE2B

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Description

The DNASE2B (deoxyribonuclease 2 beta) is a protein-coding gene located on chromosome 1.

DNASE2B, also known as DNase II-like acid DNase, hydrolyzes DNA under acidic conditions without requiring divalent cations for activity. It plays a role in the degradation of nuclear DNA during lens cell differentiation.

DNASE2B is also known as DLAD.

Associated Diseases

• granular corneal dystrophy type II
• early-onset non-syndromic cataract
• cataract
• cataract 12 multiple types
• aniridia
• cataract 8 multiple types
• gelatinous drop-like corneal dystrophy
• retinitis pigmentosa
• pulverulent cataract
• achromatopsia
• isolated ectopia lentis
• X-linked corneal dermoid
• Leber congenital amaurosis
• hemoglobin D disease
• familial pterygium of the conjunctiva