DNASE1L1

Description

The DNASE1L1 (deoxyribonuclease 1 like 1) is a protein-coding gene located on chromosome X.

DNASE1L1 is a human gene that encodes an enzyme called deoxyribonuclease-1-like 1. It is also known as DNaseX due to its location on the X chromosome. This enzyme is part of the deoxyribonuclease family and shares a lot of similarity with lysosomal DNase I. DNASE1L1 was discovered in the early 1990s. Like DNase I, DNASE1L1 breaks down DNA into smaller pieces, which is crucial for programmed cell death (apoptosis). This process prevents cells from dividing uncontrollably and potentially becoming cancerous. The absence of DNase activity is linked to an increase in tumor formation because apoptosis is disrupted.

DNASE1L1, also known as DNaseX, is an enzyme that plays a critical role in programmed cell death (apoptosis). It breaks down DNA into smaller fragments, preventing cells from dividing and potentially becoming cancerous. The absence of DNase activity is linked to increased tumor formation.

DNASE1L1 is also known as DNAS1L1, DNASEX, DNL1L, G4.8, XIB.

Associated Diseases

• Barth syndrome
• left ventricular noncompaction
• disorder of glycogen metabolism
• cancer
• glycogen storage disease II
• X-linked myopathy with excessive autophagy
• schizophrenia
• type 1 diabetes mellitus
• Adams-Oliver syndrome