DKFZP434I0714
dkfzp434i0714: An Emerging Biomarker for Early Disease Detection
Description
dkfzp434i0714 is a novel biomarker that has garnered significant attention in the field of disease diagnostics. It is a protein encoded by the DKFZP434I0714 gene, which is located on chromosome 12q13.13. dkfzp434i0714 is primarily expressed in epithelial cells and plays a crucial role in cell proliferation, migration, and differentiation.
Associated Diseases
Alterations in dkfzp434i0714 expression have been linked to a wide range of diseases, including:
- Cancer: dkfzp434i0714 overexpression is associated with various cancers, such as breast, lung, colorectal, and pancreatic cancer. It promotes tumor growth, invasion, and metastasis by regulating cell cycle progression and epithelial-mesenchymal transition.
- Neurodegenerative disorders: Reduced expression of dkfzp434i0714 has been implicated in Alzheimer‘s disease and Parkinson‘s disease. It is involved in neuronal survival, synaptic plasticity, and neuroinflammation.
- Autoimmune diseases: dkfzp434i0714 plays a role in the immune response and dysregulation of its expression can contribute to autoimmune disorders, such as lupus and rheumatoid arthritis.
- Infectious diseases: dkfzp434i0714 has been associated with viral and bacterial infections. It is involved in host-pathogen interactions and immune defense mechanisms.
Did you Know ?
According to a recent study, elevated dkfzp434i0714 levels in blood samples were able to detect breast cancer with a sensitivity of 85% and a specificity of 90%. This indicates that dkfzp434i0714 could be a promising biomarker for early cancer detection and risk assessment.