DHRS9
Description
The DHRS9 (dehydrogenase/reductase 9) is a protein-coding gene located on chromosome 2.
DHRS9 is a human gene that encodes the enzyme dehydrogenase/reductase SDR family member 9.
DHRS9 acts as a 3-alpha-hydroxysteroid dehydrogenase, converting 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. It also participates in retinoic acid biosynthesis from retinaldehyde. The enzyme can utilize both NADH and NADPH.
DHRS9 is also known as 3-alpha-HSD, 3ALPHA-HSD, RDH-TBE, RDH15, RDHL, RDHTBE, RETSDR8, SDR9C4, hRoDH-E2.
