DEPDC7
Description
The DEPDC7 (DEP domain containing 7) is a protein-coding gene located on chromosome 11.
DEPDC7, or DEP Domain Containing Protein 7, is a protein with an unknown function located on chromosome 11, spanning bases 33,015,863-33,033,581. Its cytogenetic location is 11p13. It also goes by other names: DEP Domain Containing 7, DJ85M6.4, Novel 58.3 KDA Protein, Protein TR2/D15, and TR2. The DEPDC7 gene is 17,718 base pairs long, with 8 exons and 9 introns. It can produce 6 different mRNA transcripts. Two functional domains are found within the gene's sequence: the DEP (Dishevelled, Egl-10, and Pleckstrin) domain and the RhoGAP domain. Transcription results in 4 alternatively spliced variants and 2 unspliced forms. Isoform 1, the longest variant, contains all 8 exons and codes for 511 amino acids. Northern blot analysis has shown that the DEPDC7 transcript is highly expressed in the liver and moderately expressed in the kidney in humans.
DEPDC7 is also known as TR2, dJ85M6.4.
