EREG
Description
The EREG (epiregulin) is a protein-coding gene located on chromosome 4.
Epiregulin (EPR) is a protein composed of 46 amino acids, encoded by the EREG gene in humans. Its structure is characterized by approximately 30% Ξ²-sheet content, with loops and turns formed by hydrogen bonding. The percentage of Ξ²-sheet varies depending on the domain. Epiregulin exhibits a typical 'all Ξ² motif' structure, where polypeptide chains form a continuous chain without crossovers. This structure also includes a Ξ² hairpin motif.
EREG is also known as EPR, ER, Ep.
