DDO
Description
The DDO (D-aspartate oxidase) is a protein-coding gene located on chromosome 6.
DDO is a human gene that encodes the enzyme D-aspartate oxidase. This enzyme plays a critical role in the metabolism of D-amino acids, particularly D-aspartate. D-aspartate is a neurotransmitter that can stimulate glutamate receptors in the brain, and DDO helps regulate its levels. DDO also protects the body from the potentially harmful effects of other D-amino acids. The gene is also known as DASOX or DASPO.
DDO has other meanings in different fields, such as the David Dunlap Observatory Catalogue in astronomy, Distant Detached Objects in astrophysics, and Dynamic Drive Overlay in computer science.
DDO selectively catalyzes the oxidative deamination of acidic amino acids, which includes D-aspartate. This process reduces the level of D-aspartate in the brain, where it can act as an agonist for glutamate receptors. DDO also protects the organism from the toxicity of D-amino acids and may have additional functions in the intestine.
DDO is also known as DASOX, DASPO, DDO-1, DDO-2.
