DCHS2

Description

The DCHS2 (dachsous cadherin-related 2) is a protein-coding gene located on chromosome 4.

The DCHS2 gene encodes the protein dachsous homolog 2, also known as protocadherin-23 (PCDH23) or cadherin-27 (CDH27). This protein has been linked to the nose angle, influencing how upturned a nose is.

This protein is involved in calcium-dependent cell adhesion.

DCHS2 is also known as CDH27, CDHJ, CDHR7, PCDH23, PCDHJ.

Associated Diseases

• thyrotoxic periodic paralysis
• pituitary stalk interruption syndrome
• multiple congenital anomalies/dysmorphic syndrome-intellectual disability
• prostate cancer