DCDC5
What is 5-alpha-dihydrotestosterone (DHT)?
5-alpha-dihydrotestosterone (DHT) is a potent androgenic steroid hormone derived from testosterone. It plays a crucial role in male sexual development and characteristics, including the growth of facial and body hair, muscle mass, and deepening of the voice. In women, DHT is produced in small amounts and contributes to certain female reproductive functions.
Description
DHT is a steroid hormone with a chemical structure similar to testosterone. It is produced by the enzyme 5-alpha-reductase, which converts testosterone to DHT. DHT binds to androgen receptors in cells, triggering genetic and biochemical responses that influence male development and physiology.
Associated Diseases
Elevated DHT levels have been linked to several health conditions, including:
- Androgenetic Alopecia (Male Pattern Baldness): DHT causes hair follicles to shrink and produce thinner, shorter hair, leading to male pattern baldness.
- Benign Prostatic Hyperplasia (BPH): DHT promotes prostate growth, and high levels can contribute to BPH, a non-cancerous enlargement of the prostate gland.
- Acne: DHT stimulates sebum production in the skin, which can lead to acne breakouts.
- Polycystic Ovary Syndrome (PCOS): Elevated DHT levels in women can contribute to PCOS, a hormonal disorder characterized by irregular menstrual cycles, weight gain, and infertility.
Did you Know ?
According to the American Hair Loss Association, approximately 50% of men will experience male pattern baldness by the age of 50, and DHT plays a significant role in this condition.
