CYTL1
Description
The CYTL1 (cytokine like 1) is a protein-coding gene located on chromosome 4.
CYTL1, also known as Protein C17, is a protein encoded by the CYTL1 gene in humans. It is a cytokine-like protein specifically found in bone marrow and cord blood mononuclear cells displaying the CD34 surface marker. Primarily known as a secretory protein expressed in CD34+ hematopoietic cells, CYTL1 is involved in regulating chondrogenesis, maintaining cartilage homeostasis, and potentially acting as a regulatory factor in embryo implantation during early pregnancy. The C17 protein family, present in vertebrates, is characterized by two conserved sequence motifs: PPTCYSR and DDC.
CYTL1, or Cytokine-like protein 1, is expressed primarily in bone marrow and cord blood mononuclear cells marked by the CD34 surface marker. Its role in chondrogenesis is significant, contributing to maintaining cartilage homeostasis. Furthermore, CYTL1 seems to play a regulatory role in embryo implantation during the early stages of pregnancy. This protein family is characterized by the presence of two conserved sequence motifs: PPTCYSR and DDC.
CYTL1 is also known as C17, C4orf4.