CYHR1
Title: Unveiling CYHR1: A Key Player in Cardiovascular Health
Description:
CYHR1, also known as cadherin-related family member 1, is a multifaceted protein that plays a crucial role in maintaining cardiovascular health. It is involved in cell adhesion, immune responses, and vascular development. Dysregulation of CYHR1 has been linked to various cardiovascular diseases, highlighting its significance in maintaining a healthy heart.
Associated Diseases:
- Atherosclerosis: CYHR1 is involved in the regulation of lipid metabolism and inflammation within the arteries. Its loss or dysfunction can promote the formation of atherosclerotic plaques, significantly increasing the risk of cardiovascular events such as heart attack and stroke.
- Myocardial Infarction (Heart Attack): CYHR1 deficiency has been shown to exacerbate myocardial damage following a heart attack. It impairs the recruitment of immune cells to the site of injury, leading to impaired wound healing and increased mortality.
- Heart Failure: CYHR1 plays a role in regulating cardiomyocyte hypertrophy and apoptosis. Its dysregulation has been associated with the development and progression of heart failure, a condition marked by a weakened and enlarged heart.
Did you Know ?
Approximately 30% of patients with premature coronary artery disease have mutations or polymorphisms in the CYHR1 gene, suggesting a strong genetic predisposition to cardiovascular complications.