CNGA2

---

Description

The CNGA2 (cyclic nucleotide gated channel subunit alpha 2) is a protein-coding gene located on chromosome X.

CNGA2, also known as Cyclic nucleotide gated channel alpha 2, is a human gene that encodes an ion channel protein.

Odorant signals are likely transmitted through a G-protein coupled cascade that uses cAMP as a second messenger. The olfactory channel is activated by cyclic nucleotides, leading to depolarization of olfactory sensory neurons.

CNGA2 is also known as CNCA, CNCA1, CNG2, OCNC1, OCNCALPHA, OCNCa.

Associated Diseases

• macrothrombocytopenia, isolated, 2, autosomal dominant
• thrombocytopenia 4
• Leber congenital amaurosis 10
• autosomal dominant macrothrombocytopenia
• platelet-type bleeding disorder 15
• platelet-type bleeding disorder 10
• asthma, nasal polyps, and aspirin intolerance
• thrombocytopenia 2
• thrombocytopenia 7
• bleeding disorder, platelet-type, 24
• Kallmann syndrome
• DIAPH1-related sensorineural hearing loss-thrombocytopenia syndrome
• autosomal dominant nonsyndromic hearing loss 1
• beta-thalassemia-X-linked thrombocytopenia syndrome
• thrombocytopenia 3
• platelet-type bleeding disorder 19