CLDN8


Description

The CLDN8 (claudin 8) is a protein-coding gene located on chromosome 21.

Claudin-8 is a protein in humans encoded by the CLDN8 gene. It belongs to the claudin family. The gene's location and details can be found on the UCSC Genome Browser.

Claudin-8 is a crucial protein for paracellular chloride transport in the kidneys. It facilitates the incorporation of CLDN4 into tight junctions within the kidney. Claudins play a vital role in eliminating the intercellular space through tight junctions, operating independently of calcium-mediated cell adhesion.

CLDN8 is also known as HEL-S-79.

Associated Diseases



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