CKB
Description
The CKB (creatine kinase B) is a protein-coding gene located on chromosome 14.
CKB, Ckb or ckb may refer to:
CKB, also known as Creatine Kinase B-type, plays a critical role in energy transfer within cells, specifically by catalyzing the reversible transfer of phosphate between ATP (adenosine triphosphate) and various phosphogens like creatine phosphate. This enzyme is essential for tissues with high and fluctuating energy demands, such as skeletal muscle, heart, brain, and spermatozoa. CKB also functions as a key regulator of adaptive thermogenesis, participating in the futile creatine cycle. Within thermogenic fat cells, CKB localizes to mitochondria and mediates the phosphorylation of creatine, initiating a cycle of phosphorylation and dephosphorylation that dissipates the energy charge of N-phosphocreatine as heat without producing any mechanical or chemical work.
CKB is also known as B-CK, BCK, CKBB, CPK-B, HEL-211, HEL-S-29.
