CHST12
Description
The CHST12 (carbohydrate sulfotransferase 12) is a protein-coding gene located on chromosome 7.
The CHST12 gene encodes Carbohydrate sulfotransferase 12, an enzyme that plays a role in the sulfation of chondroitin and dermatan sulfate. These sulfated glycosaminoglycans are crucial components of cartilage and extracellular matrices.
CHST12 is also known as C4S-2, C4ST-2, C4ST2.
Associated Diseases
- multiple sclerosis
- Gollop-Wolfgang complex
- coxopodopatellar syndrome
- tibia, hypoplasia or aplasia of, with polydactyly
- fibular aplasia-ectrodactyly syndrome
- acromesomelic dysplasia 2C, Hunter-Thompson type
- Blount disease
- hip dysplasia, Beukes type
- metaphyseal anadysplasia
- familial clubfoot due to 17q23.1q23.2 microduplication
- acromesomelic dysplasia 2B
- mesomelic dysplasia, Savarirayan type
