CHRNB3
Description
The CHRNB3 (cholinergic receptor nicotinic beta 3 subunit) is a protein-coding gene located on chromosome 8.
The CHRNB3 gene encodes for the neuronal acetylcholine receptor subunit beta-3, a protein implicated in predisposition to tobacco dependence. This receptor is involved in neurotransmission and is composed of two types of subunits: alpha and beta.
Upon binding acetylcholine, the AChR undergoes a significant conformational change affecting all subunits. This alteration triggers the opening of an ion-conducting channel across the plasma membrane.
CHRNB3 is also known as -.
