CHRD
Description
The CHRD (chordin) is a protein-coding gene located on chromosome 3.
CHRD refers to the human gene encoding the Chordin protein.
CHRD is a crucial developmental protein that plays a role in dorsalizing early vertebrate embryonic tissues. It achieves this by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes, preventing their activity.
CHRD is also known as -.
Associated Diseases
- auriculocondylar syndrome
- genito-palato-cardiac syndrome
- Treacher-Collins syndrome
- isotretinoin-like syndrome
- cleft lip/palate
- isolated Pierre-Robin syndrome
- Toriello-Carey syndrome
- chromosome 22q11.2 deletion syndrome, distal
- branchiogenic deafness syndrome
- alveolar capillary dysplasia with misalignment of pulmonary veins
- FG syndrome 1
